OSBPL8 antibody (AA 121-220)

Catalog No. ABIN872318

The Rabbit Polyclonal anti-OSBPL8 antibody is suitable to detect OSBPL8 in samples from Human. It has been validated for IF (cc), IF (p), IHC (fro) and IHC (p).

Quick Overview for OSBPL8 antibody (AA 121-220) (ABIN872318)

Target: OSBPL8 (Oxysterol Binding Protein-Like 8 (OSBPL8))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This OSBPL8 antibody is un-conjugated

Application: Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-OSBPL8 Antibody

Binding Specificity: AA 121-220

Purpose: ORP8 Polyclonal Antibody

Predicted Reactivity: Human,Mouse,Rat,Dog,Cow,Sheep,Pig,Horse,Chicken

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human ORP8

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

Target Details for OSBPL8

Target: OSBPL8 (Oxysterol Binding Protein-Like 8 (OSBPL8))

Alternative Name: Orp8

Background:

Synonyms: MST120, MSTP120, ORP 8, OSBP related protein 8, OSBP10, OSBPL8, Oxysterol binding protein like 8, Oxysterol binding protein like protein 8, Oxysterol binding protein related protein 8, OSBL8_HUMAN.

Background: ORP8 is a member of the oxysterol-binding protein related protein family. In humans, the gene family consists of 12 members, and extensive splice variation increases the number of encoded protein products substantially. The ORPs have been implicated as sterol sensors that regulate a number of cellular functions including sterol and neutral lipid metabolism, intracellular lipid transport, membrane trafficking and cell signaling. ORP8 has been recently shown to act as a sterol sensor that affects the reverse cholesterol transport process via modulation of ABCA1 expression and macrophage cholesterol efflux.

Gene ID: 114882