SIK2 antibody (AA 281-380)

Catalog No. ABIN872322

Product Details anti-SIK2 Antibody

Target: SIK2 (Salt-Inducible Kinase 2 (SIK2))

Binding Specificity: AA 281-380

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SIK2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Predicted Reactivity: Human,Mouse,Rat,Dog,Horse,Chicken,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human SNF1LK2/SIK2

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

Target Details for SIK2

Target: SIK2 (Salt-Inducible Kinase 2 (SIK2))

Alternative Name: SNF1LK2 (SIK2 Products)

Synonyms: PIG33 antibody, SC1 antibody, LOH11CR1I antibody, QIK antibody, SNF1LK2 antibody, G630080D20Rik antibody, Snf1lk2 antibody, RGD1559698 antibody, si:dkey-27p23.1 antibody, snf1lk2a antibody, SPARC like 1 antibody, salt inducible kinase 2 antibody, salt-inducible kinase 2 antibody, salt-inducible kinase 2a antibody, SPARCL1 antibody, SIK2 antibody, SLK2 antibody, Sik2 antibody, sik2a antibody

Background:

Synonyms: QIK, Qin induced kinase, Qin-induced kinase, Salt inducible kinase 2, Salt inducible protein kinase 2, Salt inducible serine/threonine kinase 2, Salt-inducible protein kinase 2, Serine/threonine protein kinase SIK2, Serine/threonine protein kinase SNF1 like kinase 2, Serine/threonine-protein kinase SIK2, Serine/threonine-protein kinase SNF1-like kinase 2, SIK 2, SIK-2, SIK2, SIK2_HUMAN, SNF1 like kinase, SNF1 like kinase 2, SNF1LK2, DKFZp434K1115, EC 2.7.11.1, KIAA0781, LOH11CR1I.

Background: Phosphorylates 'Ser-794' of IRS1 in insulin-stimulated adipocytes, potentially modulating the efficiency of insulin signal transduction. Inhibits CREB activity by phosphorylating and repressing TORCs, the CREB-specific coactivators.