SMC2 antibody (AA 401-500)

Catalog No. ABIN872430

This anti-SMC2 antibody is a Rabbit Polyclonal antibody detecting SMC2 in WB, ELISA, IF (cc), IF (p), IHC (fro) and IHC (p). Suitable for Human, Rat and Mouse.

Quick Overview for SMC2 antibody (AA 401-500) (ABIN872430)

Target: SMC2 (Structural Maintenance of Chromosomes 2 (SMC2))

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SMC2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-SMC2 Antibody

Binding Specificity: AA 401-500

Cross-Reactivity: Human, Mouse, Rat

Predicted Reactivity: Horse

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human SMC2

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

Target Details for SMC2

Target: SMC2 (Structural Maintenance of Chromosomes 2 (SMC2))

Alternative Name: SMC2

Background:

Synonyms: CAP E, CAPE, Chromosome associated protein E, Chromosome-associated protein E, FLJ10093, hCAP E, hCAP-E, hCAPE, PRO0324, SMC 2, SMC protein 2, SMC-2, SMC2, SMC2 L1, SMC2_HUMAN, SMC2L1, Structural maintenance of chromosomes SMC family member chromosome associated protein E, Structural maintenance of chromosomes 2, Structural maintenance of chromosomes 2 like 1, Structural maintenance of chromosomes 2 yeast like 1, Structural maintenance of chromosomes protein 2, XCAP E homolog, XCAP-E homolog, XCAPE homolog.

Background: Central component of the condensin complex, a complex required for conversion of interphase chromatin into mitotic-like condense chromosomes. The condensin complex probably introduces positive supercoils into relaxed DNA in the presence of type I topoisomerases and converts nicked DNA into positive knotted forms in the presence of type II topoisomerases.

Gene ID: 10592

UniProt: O95347