THAP1 antibody (AA 121-213)

Catalog No. ABIN872590

This Rabbit Polyclonal antibody specifically detects THAP1 in ELISA, IF (cc), IF (p), IHC (fro) and IHC (p). It exhibits reactivity toward Human.

Quick Overview for THAP1 antibody (AA 121-213) (ABIN872590)

Target: THAP1 (THAP Domain Containing, Apoptosis Associated Protein 1 (THAP1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This THAP1 antibody is un-conjugated

Application: ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-THAP1 Antibody

Binding Specificity: AA 121-213

Predicted Reactivity: Human,Mouse,Rat,Dog,Cow,Sheep,Chicken,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human THAP1

Isotype: IgG

Application Details

Application Notes: ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

Target Details for THAP1

Target: THAP1 (THAP Domain Containing, Apoptosis Associated Protein 1 (THAP1))

Alternative Name: THAP1

Background:

Synonyms: Nuclear proapoptotic factor, THAP 1, THAP domain containing apoptosis associated protein 1, THAP domain containing protein 1, THAP domain protein 1, THAP1_HUMAN.

Background: THAP1 contains a THAP domain, a zinc-dependent DNA-binding domain. It colocalizes with the apoptosis response protein PAWR/PAR-4 in promyelocytic leukemia (PML) nuclear bodies and is a pro-apoptopic protein that potentiates both serum-withdrawal and TNF-induced apoptosis. It is a physiologic regulator of endothelial cell proliferation and cell-cycle progression, two essential processes for angiogenesis.

Gene ID: 55145