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FAM21C antibody (AA 1201-1318)

FAM21C Reactivity: Rat IF (cc), IF (p), IHC (fro), IHC (p), ELISA Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN872706
  • Target See all FAM21C Antibodies
    FAM21C (Family with Sequence Similarity 21, Member C (FAM21C))
    Binding Specificity
    • 14
    • 2
    AA 1201-1318
    Reactivity
    • 14
    • 2
    Rat
    Host
    • 14
    • 2
    Rabbit
    Clonality
    • 16
    Polyclonal
    Conjugate
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This FAM21C antibody is un-conjugated
    Application
    • 12
    • 12
    • 2
    • 2
    • 2
    • 2
    Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), ELISA
    Cross-Reactivity
    Rat
    Predicted Reactivity
    Human,Mouse,Cow,Pig,Chicken,Rabbit
    Purification
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human FAM21C
    Isotype
    IgG
    Top Product
    Discover our top product FAM21C Primary Antibody
  • Application Notes
    ELISA 1:500-1000
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    Preservative
    ProClin
    Precaution of Use
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Storage
    4 °C,-20 °C
    Storage Comment
    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    Expiry Date
    12 months
  • Target
    FAM21C (Family with Sequence Similarity 21, Member C (FAM21C))
    Alternative Name
    Fam21c (FAM21C Products)
    Synonyms
    Fam21 antibody, NP61201 antibody, FAM21A antibody, VPEF antibody, A130095H06 antibody, C530005J20Rik antibody, D6Wsu116e antibody, fam21c antibody, wu:fb78c06 antibody, zgc:153646 antibody, WASH complex subunit 2C antibody, WASH complex subunit 2 antibody, family with sequence similarity 21, member C antibody, Washc2c antibody, WASHC2C antibody, Washc2 antibody, washc2c antibody
    Background

    Synonyms: FAM21A, Family with sequence similarity 21 member C, Hypothetical protein LOC253725, KIAA0592, Protein FAM21C, FA21C_HUMAN.

    Background: Playing a essential role in the fission of tubules that serve as transport intermediates during endosome sorting, the WASH complex is present at the surface of endosomes and functions to recruit and activate the Arp2/3 complex for induction of actin polymerization. FAM21, Putative WASH complex subunit FAM21, is a component of the WASH complex. Having undergone evolutionary duplication, four highly homologous family members exist including FAM21A, FAM21B, FAM21C and FAM21D. FAM21 links the WASH complex to endosomes and is required for WASM-dependent retromer-mediated sorting. Also, by directly interacting with CapZ, FAM21 inhibits its anti-capping activity, thereby regulating actin dynamics.

    Gene ID
    253725
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