CASP5 antibody (AA 261-360)

Catalog No. ABIN872884

This Rabbit Polyclonal antibody specifically detects CASP5 in WB, ELISA, IHC (p), IF (cc), IF (p) and IHC (fro). It exhibits reactivity toward Human and Mouse.

Quick Overview for CASP5 antibody (AA 261-360) (ABIN872884)

Target: CASP5 (Caspase 5, Apoptosis-Related Cysteine Peptidase (CASP5))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CASP5 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Product Details anti-CASP5 Antibody

Binding Specificity: AA 261-360

Cross-Reactivity: Human, Mouse

Predicted Reactivity: Rat,Dog,Cow,Pig,Horse,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human Caspase 5

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

Target Details for CASP5

Target: CASP5 (Caspase 5, Apoptosis-Related Cysteine Peptidase (CASP5))

Alternative Name: Caspase 5

Background:

Synonyms: Caspase-5 subunit p20, Apoptosis related cysteine protease, CASP 5, CASP5, Caspase-5, Caspase5, Caspase 5 apoptosis related cysteine peptidase, caspase 5 apoptosis related cysteine protease, ICE, ICErel III, ICErelIII, ICEREL III, ICERELIII, ICH 3, ICH 3 protease, ICH3, ICH3 protease, MGC141966, TY, TY protease.

Background: Caspase 5 belongs to the Ced3/ICE family of cystein proteases and is an upstream Caspase with a long prodomain. It undergoes a cleavage upon activation, leading to p20 and p10 subunits which have high homology with several other Caspases over the equivalent coding sequences.

Gene ID: 838

Pathways: Inflammasome