VPS4A antibody (AA 351-437)

Catalog No. ABIN872894

The Rabbit Polyclonal anti-VPS4A antibody has been validated for WB, ELISA, IF (cc), IF (p), IHC (p) and IHC (fro). It is suitable to detect VPS4A in samples from Human, Mouse and Fish.

Quick Overview for VPS4A antibody (AA 351-437) (ABIN872894)

Target: VPS4A (Vacuolar Protein Sorting-Associated Protein 4A (VPS4A))

Reactivity: Human, Mouse, Fish

Host: Rabbit

Clonality: Polyclonal

Conjugate: This VPS4A antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Product Details anti-VPS4A Antibody

Binding Specificity: AA 351-437

Cross-Reactivity: Fish, Human, Mouse

Predicted Reactivity: Rat,Dog,Pig,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human VPS4a

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

Target Details for VPS4A

Target: VPS4A (Vacuolar Protein Sorting-Associated Protein 4A (VPS4A))

Alternative Name: VPS4a

Background:

Synonyms: hVPS4, SKD1, SKD1 homolog, SKD2, Vacuolar protein sorting 4 homolog A, vacuolar sorting protein 4, VPS4.

Background: Involved in intracellular protein transport probably out of a prevacuolar endosomal compartment. May be involved in the release of components of the bilayered coat from the endosomal membrane. The association with ESCRT-III complex mediates the ATP-dependent disassembly of the ESCRT-III complex. In case of infection, the HIV-1 virus takes advantage of it for budding and exocytic cargos of viral proteins.

Gene ID: 27183

Pathways: Microtubule Dynamics, CXCR4-mediated Signaling Events