VPS4A antibody (N-Term)
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- Target See all VPS4A Antibodies
- VPS4A (Vacuolar Protein Sorting-Associated Protein 4A (VPS4A))
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Binding Specificity
- AA 44-77, N-Term
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This VPS4A antibody is un-conjugated
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Application
- Western Blotting (WB)
- Predicted Reactivity
- M, Rat
- Purification
- This antibody is purified through a protein A column, followed by peptide affinity purification.
- Immunogen
- This VPS4A antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 44-77amino acids from the N-terminal region of human VPS4A.
- Clone
- RB49739
- Isotype
- Ig Fraction
- Top Product
- Discover our top product VPS4A Primary Antibody
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- Application Notes
- WB: 1:1000
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- 4 °C,-20 °C
- Expiry Date
- 6 months
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- Target
- VPS4A (Vacuolar Protein Sorting-Associated Protein 4A (VPS4A))
- Alternative Name
- VPS4A (VPS4A Products)
- Synonyms
- vsp4 antibody, SKD1 antibody, SKD1A antibody, SKD2 antibody, VPS4 antibody, VPS4-1 antibody, zgc:153907 antibody, 4930589C15Rik antibody, AI325971 antibody, AW553189 antibody, vacuolar protein sorting 4 homolog A antibody, vacuolar sorting protein 4 antibody, vacuolar protein sorting 4 homolog A L homeolog antibody, vacuolar protein sorting 4a homolog A (S. cerevisiae) antibody, vacuolar protein sorting 4A antibody, VPS4A antibody, TP03_0351 antibody, vps4a antibody, vps4a.L antibody, Vps4a antibody
- Background
- Involved in late steps of the endosomal multivesicular bodies (MVB) pathway. Recognizes membrane-associated ESCRT-III assemblies and catalyzes their disassembly, possibly in combination with membrane fission. Redistributes the ESCRT-III components to the cytoplasm for further rounds of MVB sorting. MVBs contain intraluminal vesicles (ILVs) that are generated by invagination and scission from the limiting membrane of the endosome and mostly are delivered to lysosomes enabling degradation of membrane proteins, such as stimulated growth factor receptors, lysosomal enzymes and lipids. In conjunction with the ESCRT machinery also appears to function in topologically equivalent membrane fission events, such as the terminal stages of cytokinesis and enveloped virus budding (HIV-1 and other lentiviruses). Involved in cytokinesis.
- Molecular Weight
- 48898
- UniProt
- Q9UN37
- Pathways
- Microtubule Dynamics, CXCR4-mediated Signaling Events
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