Cyclin L1 antibody (AA 351-450)

Catalog No. ABIN872995

This Rabbit Polyclonal antibody specifically detects Cyclin L1 in WB, ELISA, IHC (p), IF (cc), IF (p) and IHC (fro). It exhibits reactivity toward Chimpanzee.

Quick Overview for Cyclin L1 antibody (AA 351-450) (ABIN872995)

Target: Cyclin L1 (CCNL1)

Reactivity: Chimpanzee

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Cyclin L1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Product Details anti-Cyclin L1 Antibody

Binding Specificity: AA 351-450

Cross-Reactivity: Chimpanzee

Predicted Reactivity: Human,Mouse,Rat,Dog,Cow,Sheep,Pig,Chimpanzee

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human Cyclin L/CCNL1

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

Target Details for Cyclin L1

Target: Cyclin L1 (CCNL1)

Alternative Name: Cyclin L

Background:

Synonyms: Ania 6a, BM 001, CCNL 1, CCNL1, CCNL1_HUMAN, Cyclin L ania 6a, Cyclin L, Cyclin L gamma, Cyclin L1, Cyclin-L, Cyclin-L1.

Background: Transcriptional regulator which participates in regulating the pre-mRNA splicing process. Seems to be involved in the regulation of RNA polymerase II (pol II). Functions in association with cyclin-dependent kinases (CDKs) and has a role in the second step of splicing. May be a candidate proto-oncogene in head and neck squamous cell carcinomas (HNSCC). Inhibited by the CDK-specific inhibitor p21.Tissue specificity,Ubiquitous with higher level in thymus. Overexpression in primary tumors of head and neck squamous cell carcinomas (HNSCC).

Gene ID: 57018