GMCL1L antibody (AA 351-450)

Catalog No. ABIN873019

This Rabbit Polyclonal antibody specifically detects GMCL1L in WB, IF (cc), IF (p), ELISA, IHC (fro) and IHC (p). It exhibits reactivity toward Mouse.

Quick Overview for GMCL1L antibody (AA 351-450) (ABIN873019)

Target: GMCL1L (GMCL1P1) (Germ Cell-Less, Spermatogenesis Associated 1 Pseudogene 1 (GMCL1P1))

Reactivity: Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GMCL1L antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), ELISA, Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-GMCL1L Antibody

Binding Specificity: AA 351-450

Cross-Reactivity: Mouse

Predicted Reactivity: Human,Rat,Dog,Cow,Sheep,Pig,Horse

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human GMCL1L

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

Target Details for GMCL1L

Target: GMCL1L (GMCL1P1) (Germ Cell-Less, Spermatogenesis Associated 1 Pseudogene 1 (GMCL1P1))

Alternative Name: GMCL1L

Background:

Synonyms: GCL, Germ cell less homolog 1 Drosophila like, Germ cell less protein like 1 like, GMCL 2, GMCL2, GMCLL_HUMAN.

Background: GMCL1L has a possible function in spermatogenesis. It enhances the degradation of MDM2 and increases the amount of p53 probably by modulating the nucleocytoplasmic transport. GMCL1L is also a probable substrate-specific adapter of an E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins.

Gene ID: 64396