GMCL1L antibody (AA 351-450)

Catalog No. ABIN873019

Product Details anti-GMCL1L Antibody

Target: GMCL1L (GMCL1P1) (Germ Cell-Less, Spermatogenesis Associated 1 Pseudogene 1 (GMCL1P1))

Binding Specificity: AA 351-450

Reactivity: Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GMCL1L antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), ELISA, Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Cross-Reactivity: Mouse

Predicted Reactivity: Human,Rat,Dog,Cow,Sheep,Pig,Horse

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human GMCL1L

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

Target Details for GMCL1L

Target: GMCL1L (GMCL1P1) (Germ Cell-Less, Spermatogenesis Associated 1 Pseudogene 1 (GMCL1P1))

Alternative Name: GMCL1L (GMCL1P1 Products)

Synonyms: GCL antibody, GMCL1L antibody, GMCL2 antibody, germ cell-less, spermatogenesis associated 1 pseudogene 1 antibody, GMCL1P1 antibody

Background:

Synonyms: GCL, Germ cell less homolog 1 Drosophila like, Germ cell less protein like 1 like, GMCL 2, GMCL2, GMCLL_HUMAN.

Background: GMCL1L has a possible function in spermatogenesis. It enhances the degradation of MDM2 and increases the amount of p53 probably by modulating the nucleocytoplasmic transport. GMCL1L is also a probable substrate-specific adapter of an E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins.

Gene ID: 64396