SRRM4 antibody (AA 451-611)

Catalog No. ABIN873105

This anti-SRRM4 antibody is a Rabbit Polyclonal antibody detecting SRRM4 in ELISA, WB, IF (cc), IF (p), IHC (fro) and IHC (p). Suitable for Mouse.

Quick Overview for SRRM4 antibody (AA 451-611) (ABIN873105)

Target: SRRM4 (Serine/arginine Repetitive Matrix 4 (SRRM4))

Reactivity: Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SRRM4 antibody is un-conjugated

Application: ELISA, Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-SRRM4 Antibody

Binding Specificity: AA 451-611

Cross-Reactivity: Mouse

Predicted Reactivity: Human,Rat,Dog,Cow,Sheep,Chicken

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human SRRM4

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

Target Details for SRRM4

Target: SRRM4 (Serine/arginine Repetitive Matrix 4 (SRRM4))

Alternative Name: SRRM4

Background:

Synonyms: Neural-specic serine/arginine repetitive splicing factor of 100 kDa, Neural-specic SR-related protein of 100 kDa, nSR100, Serine/arginine repetitive matrix protein 4, Srrm4, SRRM4_HUMAN.

Background: Splicing factor specifically required for neural cell differentiation. Acts in conjuction with nPTB/PTBP2 by binding directly to its regulated target transcripts and promotes neural-specific exon inclusion in many genes that function in neural cell differentiation. Required to promote the inclusion of neural-specific exon 10 in nPTB/PTBP2, leading to increased expression of neural-specific nPTB/PTBP2. Also promotes the inclusion of exon 16 in DAAM1 in neuron extracts.

Pathways: Sensory Perception of Sound