GPSM1 antibody (AA 201-300)

Catalog No. ABIN873148

This Rabbit Polyclonal antibody specifically detects GPSM1 in ELISA, IF (cc), IF (p), IHC (p) and IHC (fro). It exhibits reactivity toward Human.

Quick Overview for GPSM1 antibody (AA 201-300) (ABIN873148)

Target: GPSM1 (G-Protein Signaling Modulator 1 (GPSM1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GPSM1 antibody is un-conjugated

Application: ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Product Details anti-GPSM1 Antibody

Binding Specificity: AA 201-300

Predicted Reactivity: Human,Mouse,Rat,Sheep,Horse

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human GPSM1

Isotype: IgG

Application Details

Application Notes: ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

Target Details for GPSM1

Target: GPSM1 (G-Protein Signaling Modulator 1 (GPSM1))

Alternative Name: GPSM1

Background:

Synonyms: Activator of G-protein signaling 3,AGS3,AGS3 homolog,C10a,G protein signaling modulator 1 AGS3 like, C. elegans,G-protein-signaling modulator 1,GPSM1,GPSM1_HUMAN.

Background: Guanine nucleotide dissociation inhibitor (GDI) which functions as a receptor-independent activator of heterotrimeric G-protein signaling. Keeps G(i/o) alpha subunit in its GDP-bound form thus uncoupling heterotrimeric G-proteins signaling from G protein-coupled receptors. Controls spindle orientation and asymmetric cell fate of cerebral cortical progenitors. May also be involved in macroautophagy in intestinal cells. May play a role in drug addiction.

Gene ID: 26086

Pathways: Regulation of G-Protein Coupled Receptor Protein Signaling