RABGEF1 antibody (AA 251-350)

Catalog No. ABIN873174

This anti-RABGEF1 antibody is a Rabbit Polyclonal antibody detecting RABGEF1 in WB, ELISA, IF (cc), IF (p), IHC (p) and IHC (fro). Suitable for Human.

Quick Overview for RABGEF1 antibody (AA 251-350) (ABIN873174)

Target: RABGEF1 (RAB Guanine Nucleotide Exchange Factor (GEF) 1 (RABGEF1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RABGEF1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Product Details anti-RABGEF1 Antibody

Binding Specificity: AA 251-350

Predicted Reactivity: Human,Mouse,Rat,Dog,Cow,Pig,Horse,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human RABX5

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

Target Details for RABGEF1

Target: RABGEF1 (RAB Guanine Nucleotide Exchange Factor (GEF) 1 (RABGEF1))

Alternative Name: RABX5

Background:

Synonyms: RAB guanine nucleotide exchange factor GEF 1, Rab5 GDP/GTP exchange factor, Rab5ef, Rabaptin 5 associated exchange factor for Rab5, Rabaptin-5-associated exchange factor for Rab5, Rabex 5, Rabex-5, RABGEF 1, Rabgef1, RABX 5, RABX5, RABX5_HUMAN, RAP1, Rin 2, Rin2.

Background: Rab effector protein acting as linker between gamma-adaptin, RAB4A or RAB5A. Involved in endocytic membrane fusion and membrane trafficking of recycling endosomes. Stimulates nucleotide exchange on RAB5A. Can act as a ubiquitin ligase.

Gene ID: 27342

Pathways: Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process