MALT1 antibody (AA 631-730)

Catalog No. ABIN873227

The Rabbit Polyclonal anti-MALT1 antibody is suitable to detect MALT1 in samples from Human. It has been validated for WB, IHC (p), IF (cc), IF (p) and IHC (fro).

Quick Overview for MALT1 antibody (AA 631-730) (ABIN873227)

Target: MALT1 (Mucosa Associated Lymphoid Tissue Lymphoma Translocation Gene 1 (MALT1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MALT1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Product Details anti-MALT1 Antibody

Binding Specificity: AA 631-730

Purpose: MALT1 Polyclonal Antibody

Predicted Reactivity: Human,Mouse,Rat,Sheep,Horse,Chicken

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human MALT1

Isotype: IgG

Application Details

Application Notes: WB(1:500-1000),

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

Target Details for MALT1

Target: MALT1 (Mucosa Associated Lymphoid Tissue Lymphoma Translocation Gene 1 (MALT1))

Alternative Name: MALT1

Background:

Synonyms: Caspase like protein, DKFZp434L132, MALT 1, MALT associated translocation, MALT lymphoma associated translocation, MALT lymphoma-associated translocation, Malt1, MALT1_HUMAN, MLT 1, MLT, MLT1, Mucosa associated lymphoid tissue lymphoma translocation gene 1, Mucosa associated lymphoid tissue lymphoma translocation protein 1, Mucosa-associated lymphoid tissue lymphoma translocation protein 1, Paracaspase.

Background: This gene has been found to be recurrently rearranged in chromosomal translocation with two other genes - baculoviral IAP repeat-containing protein 3 (also known as apoptosis inhibitor 2) and immunoglobulin heavy chain locus - in mucosa-associated lymphoid tissue lymphomas. The protein encoded by this gene may play a role in NF-kappaB activation. Two alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Jul 2008].

Gene ID: 10892

Pathways: TCR Signaling, Fc-epsilon Receptor Signaling Pathway, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, BCR Signaling, Ubiquitin Proteasome Pathway, S100 Proteins