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Cyclin E1 antibody (pThr77) (AbBy Fluor® 350)

CCNE1 Reactivity: Human WB, FACS, IF (cc) Host: Rabbit Polyclonal AbBy Fluor® 350

Catalog No. ABIN878416

Datasheet as PDF

Target See all Cyclin E1 (CCNE1) Antibodies

Cyclin E1 (CCNE1)
Binding Specificity
26

16

13

11

9

8

7

6

5

3

3

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
pThr77
Reactivity
134

35

31

3

2

2

2
Human
Host
110

23

1
Rabbit
Compatible Secondaries
Clonality
103

31
Polyclonal
Conjugate
75

7

5

4

3

3

3

3

3

3

3

2

2

2

2

2

2

2

2

2

2

1

1
This Cyclin E1 antibody is conjugated to AbBy Fluor® 350
Application
88

42

41

37

28

27

18

13

9

6

3

3

3

2

2

1

1

1

1

1
Western Blotting (WB), Flow Cytometry (FACS), Immunofluorescence (Cultured Cells) (IF (cc))

Cross-Reactivity

Human

Predicted Reactivity

Mouse,Rat,Dog,Cow,Pig,Horse,Chicken,Rabbit

Purification

Purified by Protein A.

Immunogen

KLH conjugated synthetic phosphopeptide derived from human Cyclin E around the phosphorylation site of Thr77

Isotype

IgG

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anti-Cyclin E1 (CCNE1) (AA 10-176) antibody
CCNE1 Reactivity: Human WB, IHC, StM Host: Mouse Monoclonal CCNE1-2460 unconjugated

anti-Cyclin E1 (CCNE1) (AA 375-411) antibody
CCNE1 Reactivity: Human, Mouse, Rat WB, ELISA, FACS, IHC (p), IF (cc), IF (p), IHC (fro) Host: Rabbit Polyclonal unconjugated

anti-Cyclin E1 (CCNE1) (AA 1-410) antibody
CCNE1 Reactivity: Human WB, PLA Host: Rabbit Polyclonal unconjugated

anti-Cyclin E1 (CCNE1) (AA 307-410) antibody
CCNE1 Reactivity: Human, Mouse Host: Mouse Monoclonal unconjugated

anti-Cyclin E1 (CCNE1) (Thr395) antibody
CCNE1 Reactivity: Human WB, IHC, ELISA, IF Host: Rabbit Polyclonal unconjugated

anti-Cyclin E1 (CCNE1) antibody
CCNE1 Reactivity: Human IHC, ELISA, IF Host: Rabbit Monoclonal 3A5 unconjugated Recombinant Antibody

anti-Cyclin E1 (CCNE1) (C-Term) antibody
CCNE1 Reactivity: Human, Mouse, Rat WB, IHC, ELISA, IF, ICC Host: Rabbit Polyclonal unconjugated

anti-Cyclin E1 (CCNE1) (AA 373-402), (C-Term) antibody
CCNE1 Reactivity: Human WB, FACS, IHC (p) Host: Rabbit Polyclonal RB07335 unconjugated

Application Notes

FCM 1:20-100
IF(ICC) 1:50-200

Restrictions

For Research Use only
Format

Liquid

Concentration

1 μg/μL

Buffer

Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative

ProClin

Precaution of Use

This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage

-20 °C

Storage Comment

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date

12 months
Target

Cyclin E1 (CCNE1)

Alternative Name

Cyclin E (CCNE1 Products)

Background

Synonyms: CCNE 1, CCNE,CCNE1,Cyclin E1 antibody Cyclin Es,Cyclin Et,CyclinE, G1/S specic cyclin E, CCNE1_HUMAN.
Background: Cyclin E is a regulatory subunit of Cdk2 and controls G1 / S transition during the mammalian cell cycle. Multiple isoforms of Cyclin E are only expressed in tumors but not in normal tissue, suggesting a post transcriptional regulation of Cyclin E. In vitro analyses indicated that these truncated variant isoforms of Cyclin E are able to phosphorylate histone H1. Alterations in the Cyclin E protein have been implicated as indicators of worse prognosis in various cancers.

Molecular Weight

47kDa

Gene ID

898

Pathways

Cell Division Cycle, Intracellular Steroid Hormone Receptor Signaling Pathway, Nuclear Hormone Receptor Binding, Mitotic G1-G1/S Phases