Ret Proto-Oncogene antibody (pTyr1062) (AbBy Fluor® 488)

Catalog No. ABIN878696

The Rabbit Polyclonal anti-Ret Proto-Oncogene antibody has been validated for WB, IF (cc) and IF (p). It is suitable to detect Ret Proto-Oncogene in samples from Human.

Quick Overview for Ret Proto-Oncogene antibody (pTyr1062) (AbBy Fluor® 488) (ABIN878696)

Target: Ret Proto-Oncogene (RET)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Ret Proto-Oncogene antibody is conjugated to AbBy Fluor® 488

Application: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Product Details anti-Ret Proto-Oncogene Antibody (AbBy Fluor® 488)

Binding Specificity: pTyr1062

Predicted Reactivity: Human,Mouse,Rat,Dog,Cow,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic phosphopeptide derived from human Ret around the phosphorylation site of Tyr1062

Isotype: IgG

Application Details

Application Notes: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for Ret Proto-Oncogene

Target: Ret Proto-Oncogene (RET)

Alternative Name: Ret

Background:

Synonyms: C ret, Cadherin family member 12, Cadherin related family member 16, CDHF 12, CDHF12, CDHR16, ELKS Fusion gene, HSCR 1, HSCR1, Hydroxyaryl protein kinase, MEN2A, MEN2B, MTC 1, MTC1, Multiple endocrine neoplasia and medullary thyroid carcinoma 1, Oncogene RET, Proto oncogene tyrosine protein kinase receptor ret, Proto-oncogene c-Ret, Proto-oncogene tyrosine-protein kinase receptor ret, PTC, RET, RET ELE1, Ret Proto oncogene, RET transforming sequence, RET_HUMAN, RET51, RET9, tyrosine-protein kinase receptor ret.

Background: The CD4 antigen is highly expressed on human T helper cells and thymocytes, and at lower levels on monocytes and dendritic cells. This integral membrane glycoprotein of approximately 58 kDa contains four external domains (D1 to D4) that show homology to members of the immunoglobulin (Ig) superfamily. It is responsible for the recognition of the MHC class II antigen. The CD4 antibody recognizes most thymocytes and about 65 % of peripheral blood T cells.

Gene ID: 5979

Pathways: RTK Signaling, Dopaminergic Neurogenesis, Regulation of Cell Size, Tube Formation