Septin 5 antibody (AA 21-120) (Cy5.5)

Catalog No. ABIN889724

The Rabbit Polyclonal anti-Septin 5 antibody has been validated for WB, IF (cc) and IF (p). It is suitable to detect Septin 5 in samples from Human and Rat.

Quick Overview for Septin 5 antibody (AA 21-120) (Cy5.5) (ABIN889724)

Target: Septin 5 (SEPT5)

Reactivity: Human, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Septin 5 antibody is conjugated to Cy5.5

Application: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Product Details anti-Septin 5 Antibody (Cy5.5)

Binding Specificity: AA 21-120

Cross-Reactivity: Human, Rat

Predicted Reactivity: Mouse,Dog,Cow,Pig,Horse

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human CDCREL/SEPT5

Isotype: IgG

Application Details

Application Notes: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for Septin 5

Target: Septin 5 (SEPT5)

Alternative Name: Septin5

Background:

Synonyms: 5 Sep, CDCrel 1, CDCREL, CDCrel-1, CDCREL1, Cell division control related protein 1, Cell division control-related protein 1, H5 antibody HCDCREL 1, Peanut like 1, Peanut like 1 homolog, Peanut like protein 1, Peanut-like protein 1, Platelet glycoprotein Ib beta chain, PNUTL1, SEPT5, SEPT-5, SEPT 5, SEPT5_HUMAN, Septin 5, Septin5, Septin-5.

Background: This gene is a member of the septin gene family of nucleotide binding proteins, originally described in yeast as cell division cycle regulatory proteins. Septins are highly conserved in yeast, Drosophila, and mouse and appear to regulate cytoskeletal organization. Disruption of septin function disturbs cytokinesis and results in large multinucleate or polyploid cells. This gene is mapped to 22q11, the region frequently deleted in DiGeorge and velocardiofacial syndromes. A translocation involving the MLL gene and this gene has also been reported in patients with acute myeloid leukemia. Alternative splicing results in multiple transcript variants. The presence of a non-consensus polyA signal (AACAAT) in this gene also results in read-through transcription into the downstream neighboring gene (GP1BB, platelet glycoprotein Ib), whereby larger, non-coding transcripts are produced. [provided by RefSeq, Dec 2010].

Gene ID: 5413

UniProt: Q99719

Pathways: Synaptic Vesicle Exocytosis