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Septin 5 antibody (AA 1-369)

SEPT5 Reactivity: Human WB, IHC, IF Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN6147556
  • Target See all Septin 5 (SEPT5) Antibodies
    Septin 5 (SEPT5)
    Binding Specificity
    • 15
    • 15
    • 8
    • 3
    • 3
    • 2
    • 2
    • 1
    AA 1-369
    Reactivity
    • 58
    • 31
    • 14
    • 2
    Human
    Host
    • 50
    • 8
    Rabbit
    Clonality
    • 50
    • 7
    • 1
    Polyclonal
    Conjugate
    • 24
    • 5
    • 5
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    This Septin 5 antibody is un-conjugated
    Application
    • 51
    • 29
    • 26
    • 13
    • 13
    • 7
    • 6
    • 6
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
    Sequence
    MSTGLRYKSK LATPEDKQDI DKQYVGFATL PNQVHRKSVK KGFDFTLMVA GESGLGKSTL VHSLFLTDLY KDRKLLSAEE RISQTVEILK HTVDIEEKGV KLKLTIVDTP GFGDAVNNTE CWKPITDYVD QQFEQYFRDE SGLNRKNIQD NRVHCCLYFI SPFGHGLRPV DVGFMKALHE KVNIVPLIAK ADCLVPSEIR KLKERIREEI DKFGIHVYQF PECDSDEDED FKQQDRELKE SAPFAVIGSN TVVEAKGQRV RGRLYPWGIV EVENQAHCDF VKLRNMLIRT HMHDLKDVTC DVHYENYRAH CIQQMTSKLT QDSRMESPIP ILPLPTPDAE TEKLIRMKDE ELRRMQEMLQ RMKQQMQDQ
    Cross-Reactivity
    Human, Mouse, Rat
    Characteristics
    Polyclonal Antibodies
    Purification
    Affinity purification
    Immunogen
    Recombinant fusion protein containing a sequence corresponding to amino acids 1-369 of human Septin 5 (NP_002679.2).
    Isotype
    IgG
    Top Product
    Discover our top product SEPT5 Primary Antibody
  • Application Notes
    WB,1:500 - 1:2000,IHC,1:100 - 1:200,IF,1:50 - 1:200
    Comment

    HIGH QUALITY

    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C. Avoid freeze / thaw cycles.
  • Target
    Septin 5 (SEPT5)
    Alternative Name
    5-Sep (SEPT5 Products)
    Synonyms
    sept5 antibody, fj37h04 antibody, zgc:73218 antibody, wu:fj37h04 antibody, SEPT5 antibody, Cdcrel-1 antibody, Cdcrel1 antibody, Pnutl1 antibody, 5-Sep antibody, CDCrel-1A antibody, CDCREL antibody, CDCREL-1 antibody, CDCREL1 antibody, H5 antibody, HCDCREL-1 antibody, PNUTL1 antibody, septin 5a antibody, septin 5 antibody, sept5a antibody, SEPT5 antibody, sept5 antibody, Sept5 antibody
    Background
    This gene is a member of the septin gene family of nucleotide binding proteins, originally described in yeast as cell division cycle regulatory proteins. Septins are highly conserved in yeast, Drosophila, and mouse and appear to regulate cytoskeletal organization. Disruption of septin function disturbs cytokinesis and results in large multinucleate or polyploid cells. This gene is mapped to 22q11, the region frequently deleted in DiGeorge and velocardiofacial syndromes. A translocation involving the MLL gene and this gene has also been reported in patients with acute myeloid leukemia. Alternative splicing results in multiple transcript variants. The presence of a non-consensus polyA signal (AACAAT) in this gene also results in read-through transcription into the downstream neighboring gene (GP1BB, platelet glycoprotein Ib), whereby larger, non-coding transcripts are produced.,SEPT5,CDCREL,CDCREL-1,CDCREL1,H5,HCDCREL-1,PNUTL1,septin-5,Signal Transduction,Cell Biology & Developmental Biology,Cell Cycle,Immunology & Inflammation,Cytokines,Neuroscience,Neurodegenerative Diseases,5-Sep
    Molecular Weight
    39 kDa/42 kDa
    Gene ID
    5413
    UniProt
    Q99719
    Pathways
    Synaptic Vesicle Exocytosis
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