CHMP1B antibody (AA 101-199) (Cy7)

Catalog No. ABIN890541

Product Details anti-CHMP1B Antibody (Cy7)

Target: CHMP1B (Charged Multivesicular Body Protein 1B (CHMP1B))

Binding Specificity: AA 101-199

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CHMP1B antibody is conjugated to Cy7

Application: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Predicted Reactivity: Human,Mouse,Rat,Cow,Sheep,Horse,Chicken,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human CHMP1B

Isotype: IgG

Application Details

Application Notes: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for CHMP1B

Target: CHMP1B (Charged Multivesicular Body Protein 1B (CHMP1B))

Alternative Name: CHMP1B (CHMP1B Products)

Background:

Synonyms: Charged multivesicular body protein 1b, CHM1B_HUMAN, CHMP1.5, CHMP1b, chmp1b, Chromatin-modying protein 1b, hVps46-2, Vacuolar protein sorting-associated protein 46-2, Vps46-2.

Background: CHMP1B belongs to the chromatin-modifying protein/charged multivesicular body protein (CHMP) family. These proteins are components of ESCRT-III (endosomal sorting complex required for transport III), a complex involved in degradation of surface receptor proteins and formation of endocytic multivesicular bodies (MVBs). Some CHMPs have both nuclear and cytoplasmic/vesicular distributions, and one such CHMP, CHMP1A (MIM 164010), is required for both MVB formation and regulation of cell cycle progression

Gene ID: 57132