DAD1 antibody (AA 11-113) (HRP)

Catalog No. ABIN893403

Product Details anti-DAD1 Antibody (HRP)

Target: DAD1 (Defender Against Cell Death 1 (DAD1))

Binding Specificity: AA 11-113

Reactivity: Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DAD1 antibody is conjugated to HRP

Application: ELISA, Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Cross-Reactivity: Mouse

Predicted Reactivity: Human,Rat,Pig

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human DAD1

Isotype: IgG

Application Details

Application Notes: IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handling Advice: Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for DAD1

Target: DAD1 (Defender Against Cell Death 1 (DAD1))

Alternative Name: DAD1 (DAD1 Products)

Synonyms: NV18456 antibody, dad1 antibody, DAD1 antibody, ost2 antibody, DAD-1 antibody, si:ch211-9d9.5 antibody, OST2 antibody, AI323713 antibody, DEFENDER AGAINST APOPTOTIC DEATH 1 antibody, F3C3.14 antibody, F3C3_14 antibody, dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit DAD1 antibody, defender against cell death 1 antibody, hypothetical protein antibody, defender against cell death 1 S homeolog antibody, Defender against death (DAD family) protein antibody, false DAD1 antibody, Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit dad-1 antibody, LOC100115214 antibody, DAD1 antibody, dad1 antibody, CC1G_00458 antibody, CpipJ_CPIJ003512 antibody, PGTG_09898 antibody, Dad1 antibody, dad1.S antibody, ATDAD1 antibody, fdad1 antibody, dad-1 antibody

Background:

Synonyms: DAD 1, DAD-1, dad1, DAD1_HUMAN, Defender against cell death 1, Dolichyl diphosphooligosaccharide protein glycosyltransferase subunit DAD1, Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit DAD1, Oligosaccharyl transferase subunit DAD1, OST 2, OST2.

Background: Component of the N-oligosaccharyl transferase enzyme which catalyzes the transfer of a high mannose oligosaccharide from a lipid-linked oligosaccharide donor to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum (ER). Loss of the DAD1 protein triggers apoptosis.

Gene ID: 1603