DEDD antibody (AA 151-250) (HRP)

Catalog No. ABIN893815

This Rabbit Polyclonal antibody specifically detects DEDD in WB, ELISA, IHC (fro) and IHC (p). It exhibits reactivity toward Human and Rat.

Quick Overview for DEDD antibody (AA 151-250) (HRP) (ABIN893815)

Target: DEDD (Death Effector Domain Containing (DEDD))

Reactivity: Human, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DEDD antibody is conjugated to HRP

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-DEDD Antibody (HRP)

Binding Specificity: AA 151-250

Cross-Reactivity: Human, Rat

Predicted Reactivity: Mouse,Cow,Pig,Chicken

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human DEDD1

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handling Advice: Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for DEDD

Target: DEDD (Death Effector Domain Containing (DEDD))

Alternative Name: Dedd1

Background:

Synonyms: DEFT, KE05, DEDD1, FLDED1, CASP8IP1, Death effector domain-containing protein, DEDPro1, Death effector domain-containing testicular molecule, FLDED-1, DEDD

Background: A scaffold protein that directs CASP3 to certain substrates and facilitates their ordered degradation during apoptosis. May also play a role in mediating CASP3 cleavage of KRT18. Regulates degradation of intermediate filaments during apoptosis. May play a role in the general transcription machinery in the nucleus and might be an important regulator of the activity of GTF3C3. Inhibits DNA transcription in vitro (By similarity).

Gene ID: 9191

UniProt: O75618