DNASE2 antibody (AA 25-90) (FITC)

Catalog No. ABIN894202

This Rabbit Polyclonal antibody specifically detects DNASE2 in IF (cc) and IF (p). It exhibits reactivity toward Human and Mouse.

Quick Overview for DNASE2 antibody (AA 25-90) (FITC) (ABIN894202)

Target: DNASE2 (Deoxyribonuclease II, Lysosomal (DNASE2))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DNASE2 antibody is conjugated to FITC

Application: Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Product Details anti-DNASE2 Antibody (FITC)

Binding Specificity: AA 25-90

Cross-Reactivity: Human, Mouse

Predicted Reactivity: Rat,Dog,Cow,Sheep,Pig

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human DNase II alpha

Isotype: IgG

Application Details

Application Notes: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for DNASE2

Target: DNASE2 (Deoxyribonuclease II, Lysosomal (DNASE2))

Alternative Name: DNase 2 alpha

Background:

Synonyms: DNL, DNL2, DNASE2A, Deoxyribonuclease-2-alpha, Acid DNase, Deoxyribonuclease II alpha, DNase II alpha, Lysosomal DNase II, R31240_2, DNASE2

Background: Hydrolyzes DNA under acidic conditions with a preference for double-stranded DNA. Plays a major role in the degradation of nuclear DNA in cellular apoptosis during development. Necessary for proper fetal development and for definitive erythropoiesis in fetal liver, where it degrades nuclear DNA expelled from erythroid precursor cells.

Gene ID: 1777

UniProt: O00115