DUSP2 antibody (AA 201-314) (AbBy Fluor® 488)

Catalog No. ABIN894548

The Rabbit Polyclonal anti-DUSP2 antibody has been validated for IF (cc) and IF (p). It is suitable to detect DUSP2 in samples from Human.

Quick Overview for DUSP2 antibody (AA 201-314) (AbBy Fluor® 488) (ABIN894548)

Target: DUSP2 (Dual Specificity Phosphatase 2 (DUSP2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DUSP2 antibody is conjugated to AbBy Fluor® 488

Application: Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Product Details anti-DUSP2 Antibody (AbBy Fluor® 488)

Binding Specificity: AA 201-314

Predicted Reactivity: Human,Mouse,Rat,Dog,Cow,Sheep,Horse

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human DUSP2

Isotype: IgG

Application Details

Application Notes: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for DUSP2

Target: DUSP2 (Dual Specificity Phosphatase 2 (DUSP2))

Alternative Name: DUSP2

Background:

Synonyms: Dual specicity phosphatase 2, Dual specicity protein phosphatase 2, Dual specicity protein phosphatase PAC 1, DUSP 2, PAC 1, PAC1, Serine/threonine specic protein phosphatase, DUS2_HUMAN.

Background: DUSP2 is a dual-specific thr/tyr phosphatase that is a physiologically relevant MAP kinase phosphatase. The gene is located on 2q11.2-q11 and contains 4 exons that span approximately 2.3kb. Under specific stress conditions, p53 regulates transcription of PAC1 through a new p53-binding site, and that PAC1 is necessary and sufficient for p53-mediated apoptosis.

Gene ID: 1844