DUSP2 antibody (C-Term)

Catalog No. ABIN951998

The Rabbit Polyclonal anti-DUSP2 antibody is suitable to detect DUSP2 in samples from Human and Mouse. It has been validated for WB, FACS and EIA.

Quick Overview for DUSP2 antibody (C-Term) (ABIN951998)

Target: DUSP2 (Dual Specificity Phosphatase 2 (DUSP2))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DUSP2 antibody is un-conjugated

Application: Western Blotting (WB), Flow Cytometry (FACS), Enzyme Immunoassay (EIA)

Product Details anti-DUSP2 Antibody

Binding Specificity: AA 269-298, C-Term

Specificity: This antibody recognizes Human and Mouse DUSP2 (C-term).

Purification: Affinity Chromatography on Protein A

Immunogen: KLH conjugated synthetic peptide between 269~298 amino acids from the C-terminal region of Human DUSP2

Isotype: Ig Fraction

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS containing 0.09 % (W/V) Sodium Azide as preservative

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for DUSP2

Target: DUSP2 (Dual Specificity Phosphatase 2 (DUSP2))

Alternative Name: DUSP2 / PAC1

Background: DUSP2 is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the mitogen-activated protein (MAP) kinase superfamily (MAPK/ERK, SAPK/JNK, p38), which are associated with cellular proliferation and differentiation. Different members of the family of dual specificity phosphatases show distinct substrate specificities for various MAP kinases, different tissue distribution and subcellular localization, and different modes of inducibility of their expression by extracellular stimuli.Synonyms: Dual specificity protein phosphatase 2, Dual specificity protein phosphatase PAC-1, PAC-1

Molecular Weight: 34400 Da

Gene ID: 1844

NCBI Accession: NP_004409