FEM1B antibody (AA 531-627) (HRP)

Catalog No. ABIN896965

This Rabbit Polyclonal antibody specifically detects FEM1B in ELISA, IHC (p) and IHC (fro). It exhibits reactivity toward Rat.

Quick Overview for FEM1B antibody (AA 531-627) (HRP) (ABIN896965)

Target: FEM1B (Fem-1 Homolog B (FEM1B))

Reactivity: Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FEM1B antibody is conjugated to HRP

Application: ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Product Details anti-FEM1B Antibody (HRP)

Binding Specificity: AA 531-627

Cross-Reactivity: Rat

Predicted Reactivity: Human,Mouse,Cow,Sheep,Horse,Chicken,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human FEM 1B

Isotype: IgG

Application Details

Application Notes: IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handling Advice: Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for FEM1B

Target: FEM1B (Fem-1 Homolog B (FEM1B))

Alternative Name: FEM 1B

Background:

Synonyms: F1AA, F1A-ALPHA, FEM1-beta, Protein fem-1 homolog B, FEM1b, Fem-1-like death receptor-binding protein alpha, Fem-1-like in apoptotic pathway protein alpha, KIAA0396

Background: Component of an E3 ubiquitin-protein ligase complex, in which it may act as a substrate recognition subunit. Involved in apoptosis by acting as a death receptor-associated protein that mediates apoptosis. Also involved in glucose homeostasis in pancreatic islet. Functions as an adapter/mediator in replication stress-induced signaling that leads to the activation of CHEK1.

Gene ID: 10116

UniProt: Q9UK73