GPSM1 antibody (AA 201-300) (Biotin)

Catalog No. ABIN899645

The Rabbit Polyclonal anti-GPSM1 antibody has been validated for ELISA, IHC (p) and IHC (fro). It is suitable to detect GPSM1 in samples from Human.

Quick Overview for GPSM1 antibody (AA 201-300) (Biotin) (ABIN899645)

Target: GPSM1 (G-Protein Signaling Modulator 1 (GPSM1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GPSM1 antibody is conjugated to Biotin

Application: ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Product Details anti-GPSM1 Antibody (Biotin)

Binding Specificity: AA 201-300

Predicted Reactivity: Human,Mouse,Rat,Sheep,Horse

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human GPSM1

Isotype: IgG

Application Details

Application Notes: IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C for 12 months.

Expiry Date: 12 months

Target Details for GPSM1

Target: GPSM1 (G-Protein Signaling Modulator 1 (GPSM1))

Alternative Name: GPSM1

Background:

Synonyms: Activator of G-protein signaling 3,AGS3,AGS3 homolog,C10a,G protein signaling modulator 1 AGS3 like, C. elegans,G-protein-signaling modulator 1,GPSM1,GPSM1_HUMAN.

Background: Guanine nucleotide dissociation inhibitor (GDI) which functions as a receptor-independent activator of heterotrimeric G-protein signaling. Keeps G(i/o) alpha subunit in its GDP-bound form thus uncoupling heterotrimeric G-proteins signaling from G protein-coupled receptors. Controls spindle orientation and asymmetric cell fate of cerebral cortical progenitors. May also be involved in macroautophagy in intestinal cells. May play a role in drug addiction.

Gene ID: 26086

Pathways: Regulation of G-Protein Coupled Receptor Protein Signaling