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IKZF1 antibody (AA 251-360) (HRP)

This anti-IKZF1 antibody is a Rabbit Polyclonal antibody detecting IKZF1 in WB, ELISA, IHC (p) and IHC (fro). Suitable for Mouse.
Catalog No. ABIN901998

Quick Overview for IKZF1 antibody (AA 251-360) (HRP) (ABIN901998)

Target

See all IKZF1 Antibodies
IKZF1 (IKAROS Family Zinc Finger 1 (Ikaros) (IKZF1))

Reactivity

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  • 38
  • 17
  • 5
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  • 4
  • 4
  • 4
  • 4
  • 1
  • 1
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  • 1
Mouse

Host

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  • 12
  • 2
Rabbit

Clonality

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Polyclonal

Conjugate

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  • 1
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  • 1
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  • 1
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  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
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This IKZF1 antibody is conjugated to HRP

Application

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Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
  • Binding Specificity

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    AA 251-360

    Cross-Reactivity

    Mouse

    Predicted Reactivity

    Human,Rat,Chicken

    Purification

    Purified by Protein A.

    Immunogen

    KLH conjugated synthetic peptide derived from human IKAROS

    Isotype

    IgG
  • Application Notes

    WB 1:300-5000
    IHC-P 1:200-400
    IHC-F 1:100-500

    Restrictions

    For Research Use only
  • Format

    Liquid

    Concentration

    1 μg/μL

    Buffer

    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

    Preservative

    ProClin

    Precaution of Use

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    Handling Advice

    Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.

    Storage

    -20 °C

    Storage Comment

    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

    Expiry Date

    12 months
  • Target

    IKZF1 (IKAROS Family Zinc Finger 1 (Ikaros) (IKZF1))

    Alternative Name

    IKAROS

    Background

    Synonyms: IKAROS family zinc finger 1 Ikaros, PRO0758, CLL associated antigen KW 6, DNA-binding protein Ikaros, hIk 1, hIk-1, IK1, Ikaros zinc finger protein, IKAROS, Ikaros family zinc finger protein 1, Ikzf1, IKZF1_HUMAN, LYF1, Lymphoid transcription factor LyF-1, zinc finger protein subfamily 1A 1, ZNFN1A1.

    Background: Transcription regulator of hematopoietic cell differentiation. Binds gamma-satellite DNA. Binds with higher affinity to gamma satellite A. Plays a role in the development of lymphocytes, B- and T-cells. Binds and activates the enhancer (delta-A element) of the CD3-delta gene. Repressor of the TDT (terminal deoxynucleotidyltransferase) gene during thymocyte differentiation. Regulates transcription through association with both HDAC-dependent and HDAC-independent complexes. Targets the 2 chromatin-remodeling complexes, NuRD and BAF (SWI/SNF), in a single complex (PYR complex), to the beta-globin locus in adult erythrocytes. Increases normal apoptosis in adult erythroid cells. Confers early temporal competence to retinal progenitor cells (RPCs).Tissue specificity:Abundantly expressed in thymus, spleen and peripheral blood Leukocytes and lymph nodes. Lower expression in bone marrow and small intestine.

    Gene ID

    10320

    Pathways

    Production of Molecular Mediator of Immune Response
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