IL18RAP antibody (AA 15-120) (AbBy Fluor® 647)

Catalog No. ABIN902274

Cited in 1 publication. The AbBy Fluor® 647-conjugated Rabbit Polyclonal anti-IL18RAP antibody (ABIN902274) specifically detects IL18RAP in WB and FACS. The antibody is reactive with Human samples.

Quick Overview for IL18RAP antibody (AA 15-120) (AbBy Fluor® 647) (ABIN902274)

Target: IL18RAP (Interleukin 18 Receptor Accessory Protein (IL18RAP))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This IL18RAP antibody is conjugated to AbBy Fluor® 647

Application: Western Blotting (WB), Flow Cytometry (FACS)

Product Details anti-IL18RAP Antibody (AbBy Fluor® 647)

Binding Specificity: AA 15-120

Purpose: IL18R Beta Polyclonal Antibody, AbBy Fluor-647 Conjugated

Cross-Reactivity: Human

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human IL-18R beta

Isotype: IgG

Application Details

Application Notes: WB(1:300-5000), FCM(1:20-100)

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

References for anti-IL18RAP antibody (AbBy Fluor® 647) (ABIN902274)

Kobori, Hamasaki, Kitaura, Yamazaki, Nishinaka, Niwa, Nakao, Wake, Mori, Yoshino, Nishibori, Takahashi: "Interleukin-18 Amplifies Macrophage Polarization and Morphological Alteration, Leading to Excessive Angiogenesis." in: Frontiers in immunology, Vol. 9, pp. 334, (2019) (PubMed).

Target Details for IL18RAP

Target: IL18RAP (Interleukin 18 Receptor Accessory Protein (IL18RAP))

Alternative Name: IL-18R Beta/CD218b

Background:

Synonyms: ACPL, CD218b, IL-1R7, IL18RB, CDw218b, IL-1R-7, IL-18RAcP, IL-1RAcPL, IL-18Rbeta, IL-18R-beta, Interleukin-18 receptor accessory protein, IL-18 receptor accessory protein, Accessory protein-like, CD218 antigen-like family member B, IL-1R accessory protein-like, Interleukin-1 receptor 7, Interleukin-18 receptor accessory protein-like, Interleukin-18 receptor beta, IL18RAP, IL1R7

Background: Required for the high affinity binding of interleukin 18 (IL-18) to its receptor complex (By similarity). Together with IL18R1 mediates IL-18-dependent activation of NF-kappa-B and JNK.

Gene ID: 8807

UniProt: O95256