IMPDH1 antibody (AA 201-300) (AbBy Fluor® 488)

Catalog No. ABIN902678

The Rabbit Polyclonal anti-IMPDH1 antibody has been validated for WB, IF (cc) and IF (p). It is suitable to detect IMPDH1 in samples from Human, Mouse and Rat.

Quick Overview for IMPDH1 antibody (AA 201-300) (AbBy Fluor® 488) (ABIN902678)

Target: IMPDH1 (Inosine 5'-Phosphate Dehydrogenase 1 (IMPDH1))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This IMPDH1 antibody is conjugated to AbBy Fluor® 488

Application: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Product Details anti-IMPDH1 Antibody (AbBy Fluor® 488)

Binding Specificity: AA 201-300

Cross-Reactivity: Human, Mouse, Rat

Predicted Reactivity: Dog,Cow,Pig,Rabbit,Guinea Pig

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human IMPDH1

Isotype: IgG

Application Details

Application Notes: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for IMPDH1

Target: IMPDH1 (Inosine 5'-Phosphate Dehydrogenase 1 (IMPDH1))

Alternative Name: IMPDH1

Background:

Synonyms: IMDH1_HUMAN, IMP inosine monophosphate dehydrogenase 1, IMP dehydrogenase 1, IMPD 1, IMPD, IMPD1, IMPDH 1, IMPDH I, IMPDH-I, Impdh1, Inosine 5' monophosphate dehydrogenase 1, Inosine monophosphate dehydrogenase 1, Inosine-5''-monophosphate dehydrogenase 1, Inosine-5'-monophosphate dehydrogenase 1, LCA11, RP10.

Background: The protein encoded by this gene acts as a homotetramer to regulate cell growth. The encoded protein is an enzyme that catalyzes the synthesis of xanthine monophosphate (XMP) from inosine-5'-monophosphate (IMP). This is the rate-limiting step in the de novo synthesis of guanine nucleotides. Defects in this gene are a cause of retinitis pigmentosa type 10 (RP10). Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2008].

Gene ID: 3614

Pathways: Ribonucleoside Biosynthetic Process