CD207 antibody (AA 213-223) (AbBy Fluor® 350)

Catalog No. ABIN904487

The Rabbit Polyclonal anti-CD207 antibody has been validated for WB. It is suitable to detect CD207 in samples from Human, Mouse, Rat.

Quick Overview for CD207 antibody (AA 213-223) (AbBy Fluor® 350) (ABIN904487)

Target: CD207 (CD207 Molecule, Langerin (CD207))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CD207 antibody is conjugated to AbBy Fluor® 350

Application: Western Blotting (WB)

Product Details anti-CD207 Antibody (AbBy Fluor® 350)

Binding Specificity: AA 213-223

Cross-Reactivity: Mouse

Predicted Reactivity: Human,Rat

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human CD207

Isotype: IgG

Application Details

Application Notes: IF(IHC-P) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for CD207

Target: CD207 (CD207 Molecule, Langerin (CD207))

Alternative Name: Langerin/Cd207

Background:

Synonyms: CLEC4K, C-type lectin domain family 4 member K, Langerin, CD207

Background: Calcium-dependent lectin displaying mannose-binding specificity. Induces the formation of Birbeck granules (BGs), is a potent regulator of membrane superimposition and zippering. Binds to sulfated as well as mannosylated glycans, keratan sulfate (KS) and beta-glucans. Facilitates uptake of antigens and is involved in the routing and/or processing of antigen for presentation to T cells. Major receptor on primary Langerhans cells for Candida species, Saccharomyces species, and Malassezia furfur. Protects against human immunodeficiency virus-1 (HIV-1) infection. Binds to high-mannose structures present on the envelope glycoprotein which is followed by subsequent targeting of the virus to the Birbeck granules leading to its rapid degradation.

Gene ID: 50489

UniProt: Q9UJ71