MAS1 antibody (AbBy Fluor® 488)

Catalog No. ABIN905729

The Rabbit Polyclonal anti-MAS1 antibody has been validated for WB. It is suitable to detect MAS1 in samples from Human.

Quick Overview for MAS1 antibody (AbBy Fluor® 488) (ABIN905729)

Target: MAS1 (MAS1 Oncogene (MAS1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MAS1 antibody is conjugated to AbBy Fluor® 488

Application: Western Blotting (WB)

Product Details anti-MAS1 Antibody (AbBy Fluor® 488)

Cross-Reactivity: Human, Mouse

Predicted Reactivity: Rat,Dog,Cow,Sheep,Pig,Horse,Rabbit,Guinea Pig

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human MAS1

Isotype: IgG

Application Details

Application Notes: FCM 1:20-100
IF(IHC-P) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for MAS1

Target: MAS1 (MAS1 Oncogene (MAS1))

Alternative Name: Mas1

Background:

Synonyms: MAS, MGRA, Proto-oncogene Mas, MAS1

Background: Receptor for angiotensin 1-7 (By similarity). Acts specifically as a functional antagonist of AGTR1 (angiotensin-2 type 1 receptor), although it up-regulates AGTR1 receptor levels. Positive regulation of AGTR1 levels occurs through activation of the G-proteins GNA11 and GNAQ, and stimulation of the protein kinase C signaling cascade. The antagonist effect on AGTR1 function is probably due to AGTR1 being physically altered by MAS1.

Gene ID: 4142

UniProt: P04201

Pathways: ACE Inhibitor Pathway, Regulation of Carbohydrate Metabolic Process