Tumor Protein p73 antibody (AA 501-631) (AbBy Fluor® 647)

Catalog No. ABIN909831

This anti-Tumor Protein p73 antibody is a Rabbit Polyclonal antibody detecting Tumor Protein p73 in IF (p) and IF (cc). Suitable for Human, Mouse and Rat.

Quick Overview for Tumor Protein p73 antibody (AA 501-631) (AbBy Fluor® 647) (ABIN909831)

Target: Tumor Protein p73 (TP73) (Tumor Protein P73 (TP73))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Tumor Protein p73 antibody is conjugated to AbBy Fluor® 647

Application: Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunofluorescence (Cultured Cells) (IF (cc))

Product Details anti-Tumor Protein p73 Antibody (AbBy Fluor® 647)

Binding Specificity: AA 501-631

Cross-Reactivity: Human, Mouse, Rat

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from mouse Tp73 protein

Isotype: IgG

Application Details

Application Notes: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for Tumor Protein p73

Target: Tumor Protein p73 (TP73) (Tumor Protein P73 (TP73))

Alternative Name: Tp73 protein

Background:

Synonyms: p73, Tp73, TAp73, Tumor protein p73, p53-like transcription factor, p53-related protein, Trp73

Background: Participates in the apoptotic response to DNA damage. Isoforms containing the transactivation domain are pro-apoptotic, isoforms lacking the domain are anti-apoptotic and block the function of p53 and transactivating p73 isoforms. May be a tumor suppressor protein.

Gene ID: 22062

UniProt: Q9JJP2

Pathways: Regulation of Cell Size, Positive Regulation of Response to DNA Damage Stimulus