PAX5 antibody (AA 301-391) (AbBy Fluor® 488)

Catalog No. ABIN910180

This Rabbit Polyclonal antibody specifically detects PAX5 in IF (cc) and IF (p). It exhibits reactivity toward Human and Mouse.

Quick Overview for PAX5 antibody (AA 301-391) (AbBy Fluor® 488) (ABIN910180)

Target: PAX5 (Paired Box 5 (PAX5))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PAX5 antibody is conjugated to AbBy Fluor® 488

Application: Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Product Details anti-PAX5 Antibody (AbBy Fluor® 488)

Binding Specificity: AA 301-391

Cross-Reactivity: Human, Mouse

Predicted Reactivity: Rat,Cow,Pig,Chicken

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human PAX5

Isotype: IgG

Application Details

Application Notes: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for PAX5

Target: PAX5 (Paired Box 5 (PAX5))

Alternative Name: Pax5

Background:

Synonyms: B cell lineage specic activator, B cell lineage specic activator protein, B cell specic activator protein, B cell specic transcription factor, B-cell-specic transcription factor, BSAP, EBB-1, KLP, Paired box 5, Paired box gene 5 B cell lineage specic activator protein, Paired box gene 5 B cell lineage specic activator, Paired box gene 5, Paired box homeotic gene 5, Paired box protein Pax 5, Paired box protein Pax-5, Paired domain gene 5, PAX 5, PAX5, PAX5_HUMAN, Transcription factor PAX 5.

Background: The PAX5 gene is a member of the paired box (PAX) family of transcription factors. The central feature of this gene family is a novel, highly conserved DNA-binding motif, known as the paired box. The PAX proteins are important regulators in early development, and alterations in the expression of their genes are thought to contribute to neoplastic transformation. The PAX5 gene encodes the B-cell lineage specific activator protein (BSAP) that is expressed at early, but not late stages of B-cell differentiation. Its expression has also been detected in developing CNS and testis, therefore, PAX5 gene product may not only play an important role in B-cell differentiation, but also in neural development and spermatogenesis.

Gene ID: 5079