PBK antibody (AA 280-320) (AbBy Fluor® 647)

Catalog No. ABIN910216

This Rabbit Polyclonal antibody specifically detects PBK in WB. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for PBK antibody (AA 280-320) (AbBy Fluor® 647) (ABIN910216)

Target: PBK (PDZ Binding Kinase (PBK))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PBK antibody is conjugated to AbBy Fluor® 647

Application: Western Blotting (WB)

Product Details anti-PBK Antibody (AbBy Fluor® 647)

Binding Specificity: AA 280-320

Cross-Reactivity: Mouse

Predicted Reactivity: Human,Rat,Dog,Cow,Pig

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human PBK

Isotype: IgG

Application Details

Application Notes: IF(IHC-P) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for PBK

Target: PBK (PDZ Binding Kinase (PBK))

Alternative Name: Pbk

Background:

Synonyms: SPK, CT84, TOPK, HEL164, Nori-3, Lymphokine-activated killer T-cell-originated protein kinase, Cancer/testis antigen 84, MAPKK-like protein kinase, PDZ-binding kinase, Spermatogenesis-related protein kinase, T-LAK cell-originated protein kinase, PBK

Background: Phosphorylates MAP kinase p38. Seems to be active only in mitosis. May also play a role in the activation of lymphoid cells. When phosphorylated, forms a complex with TP53, leading to TP53 destabilization and attenuation of G2/M checkpoint during doxorubicin-induced DNA damage.

Gene ID: 55872

UniProt: Q96KB5