PKA antibody (AA 17-100) (AbBy Fluor® 350)

Catalog No. ABIN911263

This Rabbit Polyclonal antibody specifically detects PKA in WB, IF (cc) and IF (p). It exhibits reactivity toward Human and Mouse.

Quick Overview for PKA antibody (AA 17-100) (AbBy Fluor® 350) (ABIN911263)

Target: PKA (Protein Kinase A (PKA))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PKA antibody is conjugated to AbBy Fluor® 350

Application: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Product Details anti-PKA Antibody (AbBy Fluor® 350)

Binding Specificity: AA 17-100

Cross-Reactivity: Human, Mouse

Predicted Reactivity: Rat

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from bovine PKA

Isotype: IgG

Application Details

Application Notes: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for PKA

Target: PKA (Protein Kinase A (PKA))

Alternative Name: PKA alpha + beta

Background:

Synonyms: cAMP-dependent protein kinase catalytic subunit beta, PKA C-beta, PRKACB

Background: Mediates cAMP-dependent signaling triggered by receptor binding to GPCRs. PKA activation regulates diverse cellular processes such as cell proliferation, the cell cycle, and differentiation and regulation of microtubule dynamics, chromatin condensation and decondensation, nuclear envelope disassembly and reassembly, as well as regulation of intracellular transport mechanisms and ion flux. Regulates the abundance of compartmentalized pools of its regulatory subunits through phosphorylation of PJA2 which binds and ubiquitinates these subunits, leading to their subsequent proteolysis (By similarity).

Gene ID: 282323

UniProt: P05131

Pathways: SARS-CoV-2 Protein Interactome