TNIP3 antibody (AA 51-150) (Cy3)

Catalog No. ABIN918083

The Rabbit Polyclonal anti-TNIP3 antibody has been validated for WB, IF (cc) and IF (p). It is suitable to detect TNIP3 in samples from Mouse.

Quick Overview for TNIP3 antibody (AA 51-150) (Cy3) (ABIN918083)

Target: TNIP3 (TNFAIP3 Interacting Protein 3 (TNIP3))

Reactivity: Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TNIP3 antibody is conjugated to Cy3

Application: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Product Details anti-TNIP3 Antibody (Cy3)

Binding Specificity: AA 51-150

Cross-Reactivity: Mouse

Predicted Reactivity: Human,Rat,Cow,Sheep

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human TNFAIP3 interacting protein 3/ABIN3

Isotype: IgG

Application Details

Application Notes: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for TNIP3

Target: TNIP3 (TNFAIP3 Interacting Protein 3 (TNIP3))

Alternative Name: TNFAIP3 interacting protein 3

Background:

Synonyms: Listeria induced, A20-binding inhibitor of NF-kappa-B activation 3, ABIN-3, ABIN-3 beta, FLJ21162, LIND, Listeria induced gene protein, TNFAIP3 interacting protein 3, TNFAIP3-interacting protein 3 beta, TNIP3, TNIP3 beta, TNIP3_HUMAN.

Background: ABIN-3 is a member of the A20-binding inhibitor of NF-kappaB activation (ABIN) protein family. Similar to the previously characterized human ABINs (ABIN-1 and ABIN-2), ABIN-3 can bind to A20 and inhibit NF-kappaB activation. In contrast, mouse ABIN-3 is incapable of inhibiting NF-kappaB activation by proinflammatory stimuli because the protein lacks a complete ABIN homology domain, which is required for the funcitonal activity of human ABIN-3.

Gene ID: 7128

Pathways: Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin