VASP antibody (AA 251-350) (AbBy Fluor® 647)

Catalog No. ABIN919484

The Rabbit Polyclonal anti-VASP antibody is suitable to detect VASP in samples from Human. It has been validated for WB, IF (cc) and IF (p).

Quick Overview for VASP antibody (AA 251-350) (AbBy Fluor® 647) (ABIN919484)

Target: VASP (Vasodilator-Stimulated phosphoprotein (VASP))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This VASP antibody is conjugated to AbBy Fluor® 647

Application: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Product Details anti-VASP Antibody (AbBy Fluor® 647)

Binding Specificity: AA 251-350

Purpose: VASP Polyclonal Antibody, AbBy Fluor-647 Conjugated

Cross-Reactivity: Human, Mouse, Rat

Predicted Reactivity: Dog,Cow

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human VASP

Isotype: IgG

Application Details

Application Notes: WB(1:300-5000), IF(IHC-P)(1:50-200), IF(IHC-F)(1:50-200), IF(ICC)(1:50-200)

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for VASP

Target: VASP (Vasodilator-Stimulated phosphoprotein (VASP))

Alternative Name: VASP

Background:

Synonyms: Vasodilator stimulated phosphoprotein_ Vasodilator-stimulated phosphoprotein_ VASP_ VASP_HUMAN.

Background: Vasodilator-stimulated phosphoprotein (VASP) is a member of the Ena-VASP protein family. Ena-VASP family members contain an EHV1 N-terminal domain that binds proteins containing E/DFPPPPXD/E motifs and targets Ena-VASP proteins to focal adhesions. In the mid-region of the protein, family members have a proline-rich domain that binds SH3 and WW domain-containing proteins. Their C-terminal EVH2 domain mediates tetramerization and binds both G and F actin. VASP is associated with filamentous actin formation and likely plays a widespread role in cell adhesion and motility. VASP may also be involved in the intracellular signaling pathways that regulate integrin-extracellular matrix interactions. VASP is regulated by the cyclic nucleotide-dependent kinases PKA and PKG. [provided by RefSeq].

Gene ID: 7408

Pathways: TCR Signaling, Regulation of Actin Filament Polymerization, Tube Formation