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TLR3 antibody (Biotin)

The Mouse Monoclonal anti-TLR3 antibody has been validated for WB and FACS. It is suitable to detect TLR3 in samples from Human.
Catalog No. ABIN920708

Quick Overview for TLR3 antibody (Biotin) (ABIN920708)

Target

See all TLR3 Antibodies
TLR3 (Toll-Like Receptor 3 (TLR3))

Reactivity

  • 95
  • 71
  • 30
  • 6
  • 2
  • 1
  • 1
  • 1
Human

Host

  • 90
  • 29
  • 5
  • 2
  • 1
Mouse

Clonality

  • 93
  • 34
Monoclonal

Conjugate

  • 62
  • 16
  • 14
  • 8
  • 5
  • 5
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This TLR3 antibody is conjugated to Biotin

Application

  • 88
  • 47
  • 40
  • 35
  • 26
  • 25
  • 23
  • 13
  • 13
  • 13
  • 8
  • 5
  • 4
  • 2
  • 2
  • 1
  • 1
Western Blotting (WB), Flow Cytometry (FACS)
  • Specificity

    Reacts with TLR3.

    Sterility

    0.2 μm filtered

    Isotype

    IgG1
  • Application Notes

    Flow cytometry: (intracellular) Use at a 1:10 dilution. Western blot: Use at a 1:10 dilution.

    Restrictions

    For Research Use only
  • Format

    Liquid

    Buffer

    0.5 mL of 0.2 µm sterile filtered antibody solution at 100 µg/mL in PBS containing 0.1% protein stabilizer and 0.02% sodium azide.

    Preservative

    Sodium azide

    Precaution of Use

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Storage

    4 °C
  • Target

    TLR3 (Toll-Like Receptor 3 (TLR3))

    Alternative Name

    TLR3

    Background

    Toll-like receptors (TLR) are highly conserved throughout evolution and have been implicated in the innate defence to many pathogens. In Drosophila toll is required for the anti-fungal response, while the related 18-wheeler is involved in antibacterial defences. In mammals, TLR identified as type I membrane signalling receptors with pattern recognition capabilies, have been implicated in the innate host defence to pathogens. As investigated so far all functional characterized TLR signal via the TLR/IL-1 receptor (IL-1R) pathway where recruitment of MyD88 seems to be essential. Viral replication within infected cells results in generation of dsRNA which can stimulate immune cells. Recent data show that TLR3 in viral recognition and innate defence.

    Pathways

    TLR Signaling, Activation of Innate immune Response, Hepatitis C, Toll-Like Receptors Cascades
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