Reactivity: Human, Rat, Mouse
IP
Host: Sheep
Polyclonal
unconjugated
Application Notes
Immunoprecipitation: Use at 1-10 ug/ml (reacts with the catalytically active form of SAP kinase).
Restrictions
For Research Use only
Storage
4 °C
Target
SAP Kinase
Alternative Name
SAP-Kinase
Background
SAP kinase is induced by stress agonists such as UV irradiation, heat shock and inflammatory cytokines. These stress stimuli result in the phoshorylation of and enzymatic activation of Stress Activated Protein Kinases (SAP kinases). Three SAP kinase genes are known to exist, alpha, beta and gamma, which are differentially spliced giving 10 gene products in total.