MEF2C antibody (N-Term)

Catalog No. ABIN925847

The Rabbit Polyclonal anti-MEF2C antibody is suitable to detect MEF2C in samples from Human, Mouse, Rat, Pig, Zebrafish (Danio rerio), Dog, Cow and Xenopus laevis. It has been validated for WB.

Quick Overview for MEF2C antibody (N-Term) (ABIN925847)

Target: MEF2C (Myocyte Enhancer Factor 2C (MEF2C))

Reactivity: Human, Mouse, Rat, Pig, Zebrafish (Danio rerio), Dog, Cow, Xenopus laevis

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MEF2C antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-MEF2C Antibody

Binding Specificity: N-Term

Cross-Reactivity: Rat (Rattus), Dog (Canine), Human, Pig (Porcine), Zebrafish (Brachydanio rerio), Frog, Cow (Bovine)

Immunogen: MEF2 C antibody was raised in rabbit using the N terminal of MEF2 as the immunogen

Application Details

Application Notes: WB: 2.5 µg/mL
Optimal conditions should be determined by the investigator.

Comment:

MEF2C Blocking Peptide, (ABIN5614722), is also available for use as a blocking control in assays to test for specificity of this MEF2C antibody

Restrictions: For Research Use only

Handling

Format: Lyophilized

Concentration: Lot specific

Buffer: Lyophilized powder. Add 100 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.

Handling Advice: Avoid repeated freeze/thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: Store at 4 °C, following reconstitution, aliquot and store at -20 °C.

Target Details for MEF2C

Target: MEF2C (Myocyte Enhancer Factor 2C (MEF2C))

Alternative Name: MEF2C

Background: This locus encodes a member of the MADS box transcription enhancer factor 2 (MEF2) family of proteins, which play a  role in myogenesis. The encoded protein, MEF2 polypeptide C, has both trans-activating and DNA binding activities.  This protein may play a role in maintaining the differentiated state of muscle cells. Mutations and deletions at this locus have been associated with severe mental retardation, stereotypic movements, epilepsy, and cerebral malformation. Synonyms: Polyclonal MEF2C antibody, Anti-MEF2C antibody.

Pathways: Neurotrophin Signaling Pathway, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Carbohydrate Homeostasis, Chromatin Binding, Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development, Toll-Like Receptors Cascades, BCR Signaling