Kdm6b antibody (Middle Region)

Catalog No. ABIN925949

The Rabbit Polyclonal anti-Kdm6b antibody has been validated for WB. It is suitable to detect Kdm6b in samples from Human, Mouse, Rat, Dog and Xenopus laevis.

Quick Overview for Kdm6b antibody (Middle Region) (ABIN925949)

Target: Kdm6b (Lysine (K)-Specific Demethylase 6B (Kdm6b))

Reactivity: Human, Mouse, Rat, Dog, Xenopus laevis

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Kdm6b antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-Kdm6b Antibody

Binding Specificity: Middle Region

Cross-Reactivity: Mouse (Murine), Rat (Rattus), Dog (Canine), Frog

Immunogen: JMJD3 antibody was raised in rabbit using the middle region of JMJD3 as the immunogen

Application Details

Application Notes: WB: 1.25 µg/mL
Optimal conditions should be determined by the investigator.

Comment:

JMJD3 Blocking Peptide, , is also available for use as a blocking control in assays to test for specificity of this JMJD3 antibody

Restrictions: For Research Use only

Handling

Format: Lyophilized

Concentration: Lot specific

Buffer: Lyophilized powder. Add 100 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.

Handling Advice: Avoid repeated freeze/thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: Store at 4 °C, following reconstitution, aliquot and store at -20 °C.

Target Details for Kdm6b

Target: Kdm6b (Lysine (K)-Specific Demethylase 6B (Kdm6b))

Alternative Name: JMJD3

Background: JMJD3 is a histone demethylase that specifically demethylates 'Lys-27' of histone H3, thereby playing a central role in histone code. It plays a central role in regulation of posterior development, by regulating HOX gene expression. It is involved in inflammatory response by participating in macrophage differentiation in case of inflammation by regulating gene expression and macrophage differentiation. Synonyms: Polyclonal JMJD3 antibody, Anti-JMJD3 antibody, jumonji domain containing 3, histone lysine demethylase antibody, KIAA0346 antibody.

Pathways: Warburg Effect