CPB2
Reactivity: Human
WB
Host: Rabbit
Polyclonal
unconjugated
Application Notes
Optimal conditions should be determined byt he investigator.
Restrictions
For Research Use only
Format
Liquid
Concentration
Lot specific
Buffer
Supplied in liquid form in a buffered stabilizer solution containing 50 % (v/v) glycerol.
Handling Advice
Avoid repeated freeze/thaw cycles. Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase. Product will become viscous but will not freeze. Avoid storage in frost-free freezers. Allow product to warm to room temperature and gently mix before use. Dilute only prior to immediate use.
Carboxypeptidases are enzymes that hydrolyze C-terminal peptide bonds. The carboxypeptidase family includes metallo-, serine, and cysteine carboxypeptidases. According to their substrate specificity, these enzymes are referred to as carboxypeptidase A (cleaving aliphatic residues) or carboxypeptidase B (cleaving basic amino residues). CPB2 is activated by trypsin and acts on carboxypeptidase B substrates. After thrombin activation, the mature protein downregulates fibrinolysis. Synonyms: Polyclonal TAFI antibody, Anti-TAFI antibody, Carboxypeptidase B2 antibody, CPB2 antibody, CPU antibody, PCPB antibody.