IL-18 antibody (C-Term)

Catalog No. ABIN926587

This Rabbit Polyclonal antibody specifically detects IL-18 in WB. It exhibits reactivity toward Human.

Quick Overview for IL-18 antibody (C-Term) (ABIN926587)

Target: IL-18 (IL18) (Interleukin 18 (IL18))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This IL-18 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-IL-18 Antibody

Binding Specificity: C-Term

Purification: Purified

Immunogen: IL18 antibody was raised in rabbit using the C terminal of IL18 as the immunogen

Application Details

Application Notes: Optimal conditions should be determined by the investigator.

Comment:

IL18 Blocking Peptide, (ABIN939381), is also available for use as a blocking control in assays to test for specificity of this IL18 antibody

Restrictions: For Research Use only

Handling

Format: Lyophilized

Concentration: Lot specific

Buffer: Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.

Handling Advice: Avoid repeated freeze/thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: Store at 4 °C, following reconstitution, aliquot and store at -20 °C.

Target Details for IL-18

Target: IL-18 (IL18) (Interleukin 18 (IL18))

Alternative Name: IL18

Background: The protein encoded by this gene is a proinflammatory cytokine. This cytokine can induce the IFN-gamma production of T cells. The combination of this cytokine and IL12 has been shown to inhibit IL4 dependent IgE and IgG1 production, and enhance IgG2a production of B cells. IL-18 binding protein (IL18BP) can specifically interact with this cytokine, and thus negatively regulate its biological activity. Synonyms: Polyclonal IL18 antibody, Anti-IL18 antibody, interleukin 18, interferon-gamma-inducing factor antibody, IGIF antibody, IL-18 antibody, IL-1g antibody, IL1F4 antibody, MGC12320 antibody.

Pathways: Cellular Response to Molecule of Bacterial Origin, Activated T Cell Proliferation, Cancer Immune Checkpoints, Inflammasome