AKR1D1 antibody (Middle Region)

Catalog No. ABIN926610

Product Details anti-AKR1D1 Antibody

Target: AKR1D1 (Aldo-Keto Reductase Family 1, Member D1 (AKR1D1))

Binding Specificity: Middle Region

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This AKR1D1 antibody is un-conjugated

Application: Western Blotting (WB)

Purification: Purified

Immunogen: AKR1 D1 antibody was raised in rabbit using the middle region of AKR1 1 as the immunogen

Application Details

Application Notes: Optimal conditions should be determined by the investigator.

Comment:

AKR1D1 Blocking Peptide, catalog no. 33R-10271, is also available for use as a blocking control in assays to test for specificity of this AKR1D1 antibody

Restrictions: For Research Use only

Handling

Format: Lyophilized

Concentration: Lot specific

Buffer: Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.

Handling Advice: Avoid repeated freeze/thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: Store at 4 °C, following reconstitution, aliquot and store at -20 °C.

Target Details for AKR1D1

Target: AKR1D1 (Aldo-Keto Reductase Family 1, Member D1 (AKR1D1))

Alternative Name: AKR1D1 (AKR1D1 Products)

Synonyms: 3o5bred antibody, CBAS2 antibody, SRD5B1 antibody, 3-oxo-5-beta-steroid 4-dehydrogenase-like antibody, aldo-keto reductase family 1 member D1 antibody, aldo-keto reductase family 1, member D1 antibody, aldo-keto reductase family 1, member D1 (delta 4-3-ketosteroid-5-beta-reductase) antibody, LOC491379 antibody, AKR1D1 antibody, Akr1d1 antibody

Background: The enzyme encoded by this gene is responsible for the catalysis of the 5-beta-reduction of bile acid intermediates and steroid hormones carrying a delta(4)-3-one structure. Deficiency of this enzyme may contribute to hepatic dysfunction. Three transcript variants encoding different isoforms have been found for this gene. Other variants may be present, but their full-length natures have not been determined yet. Synonyms: Polyclonal AKR1D1 antibody, Anti-AKR1D1 antibody, aldo-keto reductase family 1, member D1, delta 4-3-ketosteroid-5-beta-reductase antibody, 3o5bred antibody, CBAS2 antibody, SRD5B1 antibody.

Pathways: Steroid Hormone Biosynthesis, C21-Steroid Hormone Metabolic Process, Monocarboxylic Acid Catabolic Process