RCC1 antibody (C-Term)

Catalog No. ABIN926713

This Rabbit Polyclonal antibody specifically detects RCC1 in WB. It exhibits reactivity toward Human.

Quick Overview for RCC1 antibody (C-Term) (ABIN926713)

Target: RCC1 (Regulator of Chromosome Condensation 1 (RCC1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RCC1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-RCC1 Antibody

Binding Specificity: C-Term

Purification: Purified

Immunogen: RCC1 antibody was raised in rabbit using the C terminal of RCC1 as the immunogen

Application Details

Application Notes: Optimal conditions should be determined by the investigator.

Comment:

RCC1 Blocking Peptide, (ABIN937009), is also available for use as a blocking control in assays to test for specificity of this RCC1 antibody

Restrictions: For Research Use only

Handling

Format: Lyophilized

Concentration: Lot specific

Buffer: Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.

Handling Advice: Avoid repeated freeze/thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: Store at 4 °C, following reconstitution, aliquot and store at -20 °C.

Target Details for RCC1

Target: RCC1 (Regulator of Chromosome Condensation 1 (RCC1))

Alternative Name: RCC1

Background: RCC1 is a Guanine-nucleotide releasing factor that promotes the exchange of Ran-bound GDP by GTP. Involved in the regulation of onset of chromosome condensation in the S phase. Binds both to the nucleosomes and double-stranded DNA. RCC1-Ran complex (together with other proteins) acts as a component of a signal transmission pathway that detects unreplicated DNA. Plays a key role in nucleo-cytoplasmic transport, mitosis and nuclear-envelope assembly. Synonyms: Polyclonal RCC1 antibody, Anti-RCC1 antibody, regulator of chromosome condensation 1 antibody, CHC1 antibody, RCC1-I antibody.

Pathways: Chromatin Binding, Protein targeting to Nucleus