EIF6 antibody (N-Term)

Catalog No. ABIN926731

This Rabbit Polyclonal antibody specifically detects EIF6 in WB. It exhibits reactivity toward Human.

Quick Overview for EIF6 antibody (N-Term) (ABIN926731)

Target: EIF6 (Eukaryotic Translation Initiation Factor 6 (EIF6))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This EIF6 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-EIF6 Antibody

Binding Specificity: N-Term

Purification: Purified

Immunogen: EIF6 antibody was raised in rabbit using the N terminal of EIF6 as the immunogen

Application Details

Application Notes: Optimal conditions should be determined by the investigator.

Comment:

EIF6 Blocking Peptide, (ABIN936999), is also available for use as a blocking control in assays to test for specificity of this EIF6 antibody

Restrictions: For Research Use only

Handling

Format: Lyophilized

Concentration: Lot specific

Buffer: Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.

Handling Advice: Avoid repeated freeze/thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: Store at 4 °C, following reconstitution, aliquot and store at -20 °C.

Target Details for EIF6

Target: EIF6 (Eukaryotic Translation Initiation Factor 6 (EIF6))

Alternative Name: EIF6

Background: Hemidesmosomes are structures which link the basal lamina to the intermediate filament cytoskeleton. An important functional component of hemidesmosomes is the integrin beta-4 subunit (ITGB4), a protein containing two fibronectin type III domains. The protein encoded by this gene binds to the fibronectin type III domains of ITGB4 and may help link ITGB4 to the intermediate filament cytoskeleton. The encoded protein, which is insoluble and found both in the nucleus and in the cytoplasm, can function as a translation initiation factor and prevent the association of the 40S and 60S ribosomal subunits. Synonyms: Polyclonal EIF6 antibody, Anti-EIF6 antibody, eukaryotic translation initiation factor 6 antibody, 2 antibody, CAB antibody, EIF3A antibody, ITGB4BP antibody, b antibody, b(2)gcn antibody, gcn antibody, p27BBP antibody.

Pathways: Ribonucleoprotein Complex Subunit Organization, Ribosome Assembly