Dematin antibody (Middle Region)

Catalog No. ABIN926778

Product Details anti-Dematin Antibody

Target: Dematin (EPB49) (erythrocyte Membrane Protein Band 4.9 (Dematin) (EPB49))

Binding Specificity: Middle Region

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Dematin antibody is un-conjugated

Application: Western Blotting (WB)

Purification: Purified

Immunogen: EPB49 antibody was raised in rabbit using the middle region of EPB49 as the immunogen

Application Details

Application Notes: Optimal conditions should be determined by the investigator.

Comment:

EPB49 Blocking Peptide, catalog no. 33R-10351, is also available for use as a blocking control in assays to test for specificity of this EPB49 antibody

Restrictions: For Research Use only

Handling

Format: Lyophilized

Concentration: Lot specific

Buffer: Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.

Handling Advice: Avoid repeated freeze/thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: Store at 4 °C, following reconstitution, aliquot and store at -20 °C.

Target Details for Dematin

Target: Dematin (EPB49) (erythrocyte Membrane Protein Band 4.9 (Dematin) (EPB49))

Alternative Name: EPB49 (EPB49 Products)

Synonyms: MGC80597 antibody, MGC108072 antibody, EPB49 antibody, DMT antibody, AI325486 antibody, Epb4.9 antibody, Epb49 antibody, dematin antibody, dematin actin binding protein L homeolog antibody, dematin actin binding protein antibody, dmtn.L antibody, DMTN antibody, dmtn antibody, Dmtn antibody

Background: Dematin, or EPB49, is an actin-bundling protein originally identified in the erythroid membrane skeleton. Its actin-bundling activity is abolished upon phosphorylation by cAMP-dependent protein kinase and is restored after dephosphorylation. Synonyms: Polyclonal EPB49 antibody, Anti-EPB49 antibody, erythrocyte membrane protein band 4.9, dematin antibody, DMT antibody, FLJ78462 antibody, FLJ98848 antibody.

Pathways: Regulation of Actin Filament Polymerization