Cyclin T1 antibody (N-Term)

Catalog No. ABIN926896

Product Details anti-Cyclin T1 Antibody

Target: Cyclin T1 (CCNT1)

Binding Specificity: N-Term

Reactivity: Human, Mouse, Rat, Cow, Dog, Pig, Xenopus laevis, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Cyclin T1 antibody is un-conjugated

Application: Western Blotting (WB)

Cross-Reactivity: Mouse (Murine), Rat (Rattus), Cow (Bovine), Dog (Canine), Frog, Pig (Porcine), Zebrafish (Brachydanio rerio)

Purification: Purified

Immunogen: CCNT1 antibody was raised in rabbit using the N terminal of CCNT1 as the immunogen

Application Details

Application Notes: WB: 0.2-1 µg/mL
Optimal conditions should be determined by the investigator.

Comment:

CCNT1 Blocking Peptide, catalog no. 33R-2426, is also available for use as a blocking control in assays to test for specificity of this CCNT1 antibody

Restrictions: For Research Use only

Handling

Format: Lyophilized

Concentration: Lot specific

Buffer: Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.

Handling Advice: Avoid repeated freeze/thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: Store at 4 °C, following reconstitution, aliquot and store at -20 °C.

Target Details for Cyclin T1

Target: Cyclin T1 (CCNT1)

Alternative Name: CCNT1 (CCNT1 Products)

Synonyms: CG6292 antibody, Dmcyclin T antibody, Dmel\\CG6292 antibody, ORE-14 antibody, P-TEFb antibody, anon-74EFc antibody, dT antibody, p124 antibody, Cyclin-T1 antibody, ccnt antibody, cyct1 antibody, CCNT antibody, CYCT1 antibody, HIVE1 antibody, 2810478G24Rik antibody, AI115585 antibody, CycT1 antibody, fi75b02 antibody, si:dkey-18f23.10 antibody, wu:fi75b02 antibody, Cyclin T antibody, cyclin T1 antibody, cyclin T1 L homeolog antibody, CycT antibody, CCNT1 antibody, ccnt1 antibody, Ccnt1 antibody, ccnt1.L antibody

Background: CCNT1 belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. This cyclin tightly associates with CDK9 kinase, and was found to be a major subunit of the transcription elongation factor p-TEFb. The kinase complex containing this cyclin and the elongation factor can interact with, and act as a cofactor of human immunodeficiency virus type 1 (HIV-1) Tat protein, and was shown to be both necessary and sufficient for full activation of viral transcription. Synonyms: Polyclonal CCNT1 antibody, Anti-CCNT1 antibody, cyclin T1 antibody, CCNT antibody, CYCT1 antibody.