CXCR6 antibody (N-Term)

Catalog No. ABIN926924

Product Details anti-CXCR6 Antibody

Target: CXCR6 (Chemokine (C-X-C Motif) Receptor 6 (CXCR6))

Binding Specificity: N-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CXCR6 antibody is un-conjugated

Application: Western Blotting (WB)

Purification: Purified

Immunogen: CXCR6 antibody was raised in rabbit using the N terminal of CXCR6 as the immunogen

Application Details

Application Notes: WB: 0.2-1 µg/mL
Optimal conditions should be determined by the investigator.

Comment:

CXCR6 Blocking Peptide, catalog no. 33R-1131, is also available for use as a blocking control in assays to test for specificity of this CXCR6 antibody

Restrictions: For Research Use only

Handling

Format: Lyophilized

Concentration: Lot specific

Buffer: Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.

Handling Advice: Avoid repeated freeze/thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: Store at 4 °C, following reconstitution, aliquot and store at -20 °C.

Target Details for CXCR6

Target: CXCR6 (Chemokine (C-X-C Motif) Receptor 6 (CXCR6))

Alternative Name: CXCR6 (CXCR6 Products)

Synonyms: BONZO antibody, CD186 antibody, STRL33 antibody, TYMSTR antibody, BB217514 antibody, C-X-C motif chemokine receptor 6 antibody, chemokine (C-X-C motif) receptor 6 L homeolog antibody, chemokine (C-X-C motif) receptor 6 antibody, CXCR6 antibody, cxcr6.L antibody, Cxcr6 antibody

Background: CXCR6 is a receptor for the C-X-C chemokine CXCL16. It is used as a coreceptor by SIVs and by strains of HIV-2 and m-tropic HIV-1.The CXCR6/AKT/mTOR pathway plays a central role in the development of prostate cancer. CXCR6 and CXCR3 act coordinately with respective ligands and are involved in the pathophysiology of Juvenile Idiopathic Arthritis-associated inflammatory processes. The CXCL16-CXCR6-system express in human schwannomas of different localization and in malignant peripheral nerve sheath tumors. The protein may play an important role in the retention of T cells within the lung. Synonyms: Polyclonal CXCR6 antibody, Anti-CXCR6 antibody, chemokine, C-X-C motif receptor 6 antibody, BONZO antibody, CD186 antibody, STRL33 antibody, TYMSTR antibody.