HSPD1 antibody (C-Term)

Catalog No. ABIN926938

This Rabbit Polyclonal antibody specifically detects HSPD1 in WB. It exhibits reactivity toward Human, Mouse, Rat, Dog and Cow.

Quick Overview for HSPD1 antibody (C-Term) (ABIN926938)

Target: HSPD1 (Heat Shock 60kDa Protein 1 (Chaperonin) (HSPD1))

Reactivity: Human, Mouse, Rat, Dog, Cow

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HSPD1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-HSPD1 Antibody

Binding Specificity: C-Term

Cross-Reactivity: Mouse (Murine), Rat (Rattus), Dog (Canine), Cow (Bovine)

Purification: Purified

Immunogen: HSPD1 antibody was raised in rabbit using the C terminal of HSPD1 as the immunogen

Application Details

Application Notes: WB: 0.2-1 µg/mL
Optimal conditions should be determined by the investigator.

Comment:

HSPD1 Blocking Peptide, , is also available for use as a blocking control in assays to test for specificity of this HSPD1 antibody

Restrictions: For Research Use only

Handling

Format: Lyophilized

Concentration: Lot specific

Buffer: Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.

Handling Advice: Avoid repeated freeze/thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: Store at 4 °C, following reconstitution, aliquot and store at -20 °C.

Target Details for HSPD1

Target: HSPD1 (Heat Shock 60kDa Protein 1 (Chaperonin) (HSPD1))

Alternative Name: HSPD1

Background: HSPD1 is a member of the chaperonin family. This mitochondrial protein may function as a signaling molecule in the innate immune system. It is essential for the folding and assembly of newly imported proteins in the mitochondria. This gene encodes a member of the chaperonin family. The encoded mitochondrial protein may function as a signaling molecule in the innate immune system. This protein is essential for the folding and assembly of newly imported proteins in the mitochondria. This gene is adjacent to a related family member and the region between the 2 genes functions as a bidirectional promoter. Two pseudogenes, both located on chromosome 8, have been associated with this gene. Synonyms: Polyclonal HSPD1 antibody, Anti-HSPD1 antibody, heat shock 60kDa protein 1, chaperonin antibody, CPN60 antibody, GROEL antibody, HSP60 antibody, HSP65 antibody, HuCHA60 antibody, SPG13 antibody.

Pathways: Activation of Innate immune Response, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Positive Regulation of Endopeptidase Activity